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ⓘ Eikozanoidni receptor




                                     

ⓘ Eikozanoidni receptor

Eikozanoidni receptor je integralni membranski protein koji detektuje prisustvo eikozanoidnih signalnih molekula. Većina, mada ne svi, su G protein spregnuti receptori. Primer ne-GPCR receptora koji vezuje eikozanoide je PPAR-γ.

Ovo su poznati humani eikozanoidni GPCR receptori grupisani po tipu eikozanoidnog liganda koji vezuju:

                                     

1. Leukotrien

Leukotrieni:

  • CysLT 2 Cisteinil leukotrienski receptor 2 - CYSLTR2
  • BLT 1 Leukotrienski B 4 receptor - LTB4R
  • BLT 2 Leukotrienski B 4 receptor 2 - LTB4R2
  • CysLT 1 Cisteinil leukotrienski receptor 1 - CYSLTR1
                                     

2. Prostanoid

Prostanoidi:

  • DP 2 GPR44 - GPR44
  • DP 1 Prostaglandin D2 receptor - PTGDR
  • PGD 2: DP-PGD 2
  • EP 2 -PGE 2 PTGER2 - PTGER2
  • EP 3 -PGE 2 PTGER3 - PTGER3
  • EP 1 -PGE 2 PTGER1 - PTGER1
  • EP 4 -PGE 2 PTGER4 - PTGER4
  • PGE 2
  • PGF 2α: FP-PGF 2α PTGFR - PTGFR
  • PGI 2 prostaciklin: IP-PGI 2 PTGIR - PTGIR
  • TXA 2 tromboksan: TP-TXA 2 TBXA2R - TBXA2R
                                     

3. Spoljašnje veze

  • "Leukotriene Receptors”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
  • Eicosanoid+receptors на US National Library of Medicine Medical Subject Headings MeSH
  • "Prostanoid Receptors”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.